Second large-scale Monte Carlo study for the Cherenkov Telescope Array

The Cherenkov Telescope Array (CTA) represents the next generation of ground based instruments for Very High Energy gamma-ray astronomy. It is expected to improve on the sensitivity of current instruments by an order of magnitude and provide energy coverage from 20 GeV to more than 200 TeV. In order to achieve these ambitious goals Monte Carlo (MC) simulations play a crucial role, guiding the design of CTA. Here, results of the second large-scale MC production are reported, providing a realistic estimation of feasible array candidates for both Northern and Sourthern Hemisphere sites performance, placing CTA capabilities into the context of the current generation of High Energy $\gamma$-ray detectors.Comment: In Proceedings of the 34th International Cosmic Ray Conference (ICRC2015), The Hague, The Netherlands. All CTA contributions at arXiv:1508.0589

Monte Carlo Performance Studies of Candidate Sites for the Cherenkov Telescope Array

The Cherenkov Telescope Array (CTA) is the next-generation gamma-ray observatory with sensitivity in the energy range from 20 GeV to beyond 300 TeV. CTA is proposed to consist of two arrays of 40-100 imaging atmospheric Cherenkov telescopes, with one site located in each of the Northern and Southern Hemispheres. The evaluation process for the candidate sites for CTA is supported by detailed Monte Carlo simulations, which take different attributes like site altitude and geomagnetic field configuration into account. In this contribution we present the comparison of the sensitivity and performance of the different CTA site candidates for the measurement of very-high energy gamma rays.Comment: In Proceedings of the 34th International Cosmic Ray Conference (ICRC2015), The Hague, The Netherlands. All CTA contributions at arXiv:1508.0589

Plasduino: an inexpensive, general purpose data acquisition framework for educational experiments

Based on the Arduino development platform, Plasduino is an open-source data acquisition framework specifically designed for educational physics experiments. The source code, schematics and documentation are in the public domain under a GPL license and the system, streamlined for low cost and ease of use, can be replicated on the scale of a typical didactic lab with minimal effort. We describe the basic architecture of the system and illustrate its potential with some real-life examples.Comment: 11 pages, 10 figures, presented at the XCIX conference of the Societ\`a Italiana di Fisic

Monte Carlo Performance Studies for the Site Selection of the Cherenkov Telescope Array

The Cherenkov Telescope Array (CTA) represents the next generation of ground-based instruments for very-high-energy (VHE) gamma-ray astronomy, aimed at improving on the sensitivity of current-generation experiments by an order of magnitude and providing coverage over four decades of energy. The current CTA design consists of two arrays of tens of imaging atmospheric Cherenkov telescopes, comprising Small, Medium and Large-Sized Telescopes, with one array located in each of the Northern and Southern Hemispheres. To study the effect of the site choice on the overall \gls{cta} performance and support the site evaluation process, detailed Monte Carlo simulations have been performed. These results show the impact of different site-related attributes such as altitude, night-sky background and local geomagnetic field on CTA performance for the observation of VHE gamma rays.Comment: 34 pages, 11 figures, Accepted for publication in AP

Structural transitions in the RNA 7SK 5' hairpin and their effect on HEXIM binding.

7SK RNA, as part of the 7SK ribonucleoprotein complex, is crucial to the regulation of transcription by RNA-polymerase II, via its interaction with the positive transcription elongation factor P-TEFb. The interaction is induced by binding of the protein HEXIM to the 5' hairpin (HP1) of 7SK RNA. Four distinct structural models have been obtained experimentally for HP1. Here, we employ computational methods to investigate the relative stability of these structures, transitions between them, and the effects of mutations on the observed structural ensembles. We further analyse the results with respect to mutational binding assays, and hypothesize a mechanism for HEXIM binding. Our results indicate that the dominant structure in the wild type exhibits a triplet involving the unpaired nucleotide U40 and the base pair A43-U66 in the GAUC/GAUC repeat. This conformation leads to an open major groove with enough potential binding sites for peptide recognition. Sequence mutations of the RNA change the relative stability of the different structural ensembles. Binding affinity is consequently lost if these changes alter the dominant structure

Data model issues in the Cherenkov Telescope Array project

The planned Cherenkov Telescope Array (CTA), a future ground-based Very-High-Energy (VHE) gamma-ray observatory, will be the largest project of its kind. It aims to provide an order of magnitude increase in sensitivity compared to currently operating VHE experiments and open access to guest observers. These features, together with the thirty years lifetime planned for the installation, impose severe constraints on the data model currently being developed for the project. In this contribution we analyze the challenges faced by the CTA data model development and present the requirements imposed to face them. While the full data model is still not completed we show the organization of the work, status of the design, and an overview of the prototyping efforts carried out so far. We also show examples of specific aspects of the data model currently under development.Comment: In Proceedings of the 34th International Cosmic Ray Conference (ICRC2015), The Hague, The Netherlands. All CTA contributions at arXiv:1508.0589

The Cherenkov Telescope Array Performance in Divergent Mode

Two of the Key Science Projects of the Cherenkov Telescope Array (CTA) consist in performing a deep survey of the Galactic and Extragalactic sky, providing an unbiased view of the Universe at energies above tens of GeV. To optimize the time spent to perform the Extragalactic survey, a so-called "divergent mode" of the CTA was proposed as an alternative observation strategy to the traditional parallel pointing in order to increase its instantaneous field of view. The search for transient VHE sources would also benefit from an extended field of view. In the divergent mode, each telescope points to a position in the sky that is slightly offset, in the outward direction, from the center of the field of view. In this contribution, we present the first performance estimation from full Monte Carlo simulation of possible CTA divergent mode setups